Enabling safe, high-quality health care delivery, IEEE Health Informatics/Medical Devices Communication Standards provide the interconnection and interoperation of medical devices with computerized healthcare information systems in a way that is suitable for a clinical environment. This family of standards provides real-time plug-and-play interoperability and facilitates the efficient exchange of vital signs and medical device data acquired at the point-of-care. Grouped into three categories, these standards support: Semantic interoperability, which focuses on terminologies, data models, and data sets for specific device modalities, such as, ventilators, patient vital signs monitors, and infusion pumps, Application interoperability, which identifies a set of general services that can be used by all systems to discover, configure, and exchange data across a connection, and Lower layer transport technologies. Health informatics and medical devices communication standards help advance the development and application of healthcare by securing the creation and transmission of electronic healthcare information.